Abstract: To evaluate the dynamic properties of a coupled structure based on the dynamic properties of itssubstructures, this paper investigates the dynamic substructuring issue from the perspective of responseprediction. The main idea is that the connecting forces at the interface of substructures can be xpressedby the unknown coupled structural responses, and the responses can be solved rather easily. Not onlyrigidly coupled structures but also resiliently coupled structures are investigated. In order to furthercomprehend and visualize the nature of coupling problems, the Neumann series expansion for a matrixdescribing the relation between the coupled and uncoupled substructures is also introduced in this paper. Compared with existing response prediction methods, the proposed method does not have to measure any forces, which makes it easier to apply than the others. Clearly, the frequency response function matrix of coupled structures can be derived directly based on the response prediction method. Compared with existing frequency response function synthesis methods, it is more straightforward and comprehensible. Through demonstration of two examples, it is concluded that the proposed method can deal with structural coupling problems very well.